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The changing bronchiectasis landscape: infection, biologics and anti-inflammatories

DAY 1

Chaired by Professor Melissa McDonnell (Galway) and Dr Phil Mitchelmore (Exeter)

9:00am How the microbial community impacts on immune responses in bronchiectasis 
  Professor Sanjay Chotirmal (Singapore)
9:30am Monoclonal antibodies to target pseudomonas aeruginosa: what have we learnt from the GREAT trials and mechanistic studies?
  Dr Merete Long (Oxford)
   
10.00am Targeting Type 2 inflammation in bronchiectasis: lessons from MAHALE 
  Professor Stefano Aliberti (Italy)

9:00 AM

90 MINUTE SESSION

Learning objectives 

  1. Understanding of translational science and mycobiome/resistome and microbiome. Novel data on gut-lung axis resistome in bronchiectasis.
  2. New study data on pseudomonas virulence and targeting in bronchiectasis using non-antibiotics. New data on bacterial clearance and patient quality of life using anti-microbial monoclonal antibodies.
  3. Understand study design and limitations / strengths and role of biologics to date in bronchiectasis. Data from clinical trials (not presented before) on biologics in bronchiectasis will be discussed.